Leishmania (Viannia) braziliensis isolated from the saliva of patients in a cutaneous leishmaniasis-endemic area of northeastern Brazil
AUTOR(ES)
Brito, Maria Edileuza Felinto de, Almeida, Ericka Lima, Medeiros, Angela Cristina Rapela, Werkhäuser, Roberto Pereira, Alexandre, Joanna Lucia de Almeida, Sá, Bruna Santos Lima Figueiredo, Rodrigues, Eduardo Henrique Gomes, Brandão-Filho, Sinval Pinto
FONTE
Mem. Inst. Oswaldo Cruz
DATA DE PUBLICAÇÃO
05/02/2018
RESUMO
Several studies have described the use of non-invasive collection methods, mostly based on the detection of parasite DNA, for diagnosis. However, no Leishmania specimens have been isolated from saliva. Here, we report the first isolation of Leishmania braziliensis from the saliva of humans with cutaneous leishmaniasis but without lesions on their mucosa. The isolates were obtained from salivary fluid inoculated in hamsters and were tested by multilocus enzyme electrophoresis. Seven samples from 43 patients suspected of having the disease were identified for in vivo culture. These findings suggest that saliva is a clinical sample that allows the isolation of Leishmania sp.
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