Lactococcus lactis as a Cell Factory for High-Level Diacetyl Production
AUTOR(ES)
Hugenholtz, Jeroen
FONTE
American Society for Microbiology
RESUMO
We report the engineering of Lactococcus lactis for the efficient conversion of sugar into diacetyl by combining NADH-oxidase overproduction and α-acetolactate decarboxylase inactivation. Eighty percent of the carbon flux was found to be rerouted via α-acetolactate to the production of diacetyl by preloading the cells with NADH-oxidase before their use as a cell factory.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=92266Documentos Relacionados
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