Lack of Interference of Guanosine with Ribavirin Aerosol Treatment of Influenza A Infection in Mice

AUTOR(ES)
RESUMO

Guanosine or guanosine 5′-monophosphate did not reduce the protective effect of ribavirin aerosol in influenza virus A/Aichi/68 H3N2 infection of mice. Both compounds partially interfered with the action of a wide range of ribavirin concentrations against influenza virus A/WSN replication in cell culture.

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