Lack of a relationship between serum ferritin levels and coronary atherosclerosis evaluated by coronary arteriography
AUTOR(ES)
Manfroi, Waldomiro Carlos
DATA DE PUBLICAÇÃO
2010
RESUMO
Many clinical and epidemiological studies have demonstrated the relationship between serum ferritin and ischemic heart disease. In the present study we evaluated the relationship between coronary heart disease (CHD) and serum ferritin levels in patients submitted to coronary arteriography. We evaluated 307 patients (210 (68.7%) males; median age: 60 years) who were submitted to coronary angiography, measurement of serum ferritin and identification of clinical events of ischemic heart disease. Serum ferritin is reported as quartiles. Ninety-six patients (31.27%) had normal coronary angiography (group 1) and 211 (68.73%) had coronary heart disease (group 2). Of the patients with CHD, 61 (28.9%) had serum ferritin levels higher than 194 ng/ml (4th quartile), as opposed to only 14 (14.58%) of those without CHD (P = 0.0067). In the 2nd quartile, 39 patients (18.48%) had CHD, while 35 patients (36.46%) had normal coronary arteries (P = 0.00064). Multivariate analysis of the data showed that the difference between groups was not statistically significant (P = 0.33). We conclude that there is no independent relationship between coronary heart disease and increased levels of serum ferritin.
ASSUNTO(S)
doença da artéria coronariana ferritin coronary heart disease ferritinas atherosclerosis angiografia coronária risk factors coronary arteriography
ACESSO AO ARTIGO
http://hdl.handle.net/10183/21130Documentos Relacionados
- Coronary fat content evaluated by morphometry in patients with severe atherosclerosis has no relation with serum lipid levels
- Progression of coronary atherosclerosis. Clues to pathogenesis from serial coronary arteriography.
- Relation between blood lipid levels and angiographically evaluated obstructions in coronary arteries.
- Lack of association between haemostatic variables and the presence or the extent of coronary atherosclerosis.
- Significance of serum enzyme changes after cardiac catheterization and selective coronary arteriography.