L-dopa and arousal 1
AUTOR(ES)
Horvath, Thomas B.
RESUMO
In 10 patients with Parkinsonism, treatment with L-dopa was associated with a rise in the skin conductance level and its fluctuations, an increased electromyographic activity in the frontalis muscle, and with faster reaction times. The change of skin conductance in response to a loud noise also increased and its habituation to the repetition of the stimulus was delayed. One patient developed a schizophreniform psychosis and showed high arousal and absent habituation. It is possible that dopamine is the transmitter associated with the arousal reaction and that it plays a part in the pathogenesis of schizophrenia.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=494672Documentos Relacionados
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