l-Canavanine Metabolism in Jack Bean, Canavalia ensiformis (L.) DC. (Leguminosae) 1
AUTOR(ES)
Rosenthal, Gerald A.
RESUMO
l-Canavanine, a highly toxic arginine antimetabolite, is the principal nonprotein amino acid of many leguminous plants. Labeled-precursor feeding studies, conducted primarily with [14C]carbamoyl phosphate, and utilization of the seedlings of jack bean, Canavalia ensiformis (L.) DC. (Leguminosae), have provided evidence for l-canavanine biosynthesis from l-canaline via O-ureido-l-homoserine. This reaction pathway appears to constitute an important in vivo route of canavanine production. Canavanine cleavage to canaline may represent a degradative phase of canavanine metabolism distinct from the anabolic reactions described above. Thus, while these reactions of canavanine metabolism bear analogy to the mammalian Krebs-Henseleit ornithine-urea cycle, no evidence has been obtained at present for the reutilization of canaline in ureidohomoserine formation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=426360Documentos Relacionados
- An Ontogenetic Study of Canavanine Formation in the Fruit of Jack Bean, Canavalia ensiformis (L.) DC. 1
- Investigations of Canavanine Biochemistry in the Jack Bean Plant, Canavalia ensiformis (L.) DC: II. Canavanine Biosynthesis in the Developing Plant 1
- Investigations of Canavanine Biochemistry in the Jack Bean Plant, Canavalia ensiformia (L.) DC: I. Canavanine Utilization in the Developing Plant 1
- Changes in Mitochondrial Properties Associated with Chloroplast Development in Jack Bean (Canavalia ensiformis [L] DC.) 1
- Ultrastructural Effects of Water Stress on Chloroplast Development in Jack Bean (Canavalia ensiformis [L.] DC) 1
