Jorge Lobo’s disease with malignant degeneration to squamous cell carcinoma: case report

AUTOR(ES)

Brito, Arival Cardoso de; Bittencourt, Maraya de Jesus Semblano; Gonçalves, Thainá da Silva; Cavalcante, Renata Henriques

FONTE

Anais Brasileiros de Dermatologia

DATA DE PUBLICAÇÃO

2022

RESUMO

Abstract Jorge Lobo’s disease (JLD) is a chronic, granulomatous fungal infection caused by the traumatic implantation of the fungus Lacazia loboi in the cutaneous and subcutaneous tissues, with the presence of isolated nodular and coalescent keloidal lesions. Malignant degeneration is rare. This case report describes a 64-year-old male patient with JLD for 30-years who showed a change in the aspect of a lesion in the left lower limb. Histopathological examination confirmed the progression to well-differentiated squamous cell carcinoma (SSC). JLD is highly prevalent in tropical and subtropical regions, requiring monitoring concerning the transformation into SSC in long-term lesions.

Documentos Relacionados

• Jorge Lobo’s disease
• Malignant transformation of abdominal wall endometriosis to clear cell carcinoma: case report
• Pigmented squamous cell carcinoma: case report and importance of differential diagnosis
• Jorge Lobo's disease and its relation with antigens of the hla system
• Penile squamous cell carcinoma: a review of the literature and case report treated with Mohs micrographic surgery