Intermittent chemoprophylaxis for Pneumocystis carinii pneumonia.
AUTOR(ES)
Hughes, W T
RESUMO
An intermittent regimen of trimethoprim-sulfamethoxazole was tested in the corticosteroid-treated rat model to learn whether or not administration for 3 consecutive days a week would provide prophylaxis equal to continuous daily doses. Although all of the untreated control animals acquired Pneumocystis carinii pneumonia, none of the animals given either continuous or intermittent trimethoprim-sulfamethoxazole became infected.
