Interaction of human recombination proteins Rad51 and Rad54.
AUTOR(ES)
Golub, E I
RESUMO
The cDNA for human protein HsRad54, which is a structural homolog of Saccharomyces cerevisiae recombination/repair protein Rad54, was cloned and expressed in Escherichia coli. As demonstrated by analysis in vitro and in vivo, HsRad54 protein interacts with human Rad51 recombinase. The interaction is mediated by the N-terminal domain of HsRad54 protein, which interacts with both free and DNA-bound HsRad51 protein.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=147015Documentos Relacionados
- Activities of human recombination protein Rad51
- Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA.
- Tid1/Rdh54 promotes colocalization of Rad51 and Dmc1 during meiotic recombination
- Strand pairing by Rad54 and Rad51 is enhanced by chromatin
- Interaction of p53 with the human Rad51 protein.