Inibição do crescimento da microflora oral por venenos de serpentes / GROWTH INHIBITION OF ORAL MICROFLORA BY SNAKE VENOMS

AUTOR(ES)
DATA DE PUBLICAÇÃO

2008

RESUMO

The oral health at the most of Brazilian municipalities is still a big challenge to the principles of the Brazilian Health Unique System (SUS), particularly with regard to the globalization, the equity of care and high cost involved in restorative therapy. The demand for discovery of new natural products with antibacterial activity in order to prevent dental diseases and perhaps with fewer health and financial impacts, would be very important to achieve an effective means to control the formation of a pathogenic biofilm and dental caries. The objective of this work is to study the feasibility of the use of different snakes crude venom in inhibiting the growth of Streptococcus mutans, the principal agent involved in dental caries. Our results showed that Bothrops moojeni and Bothrops jararacussu venoms were able to inhibit the growth of Streptococcus mutans and the component responsible for that inhibition appears to be the hydrogen peroxide. Though still not fully conclusive, the tests already carried out, show that snake venoms are important tools to inhibit the growth of pathogens, specifically those involved in caries diseases. MOSCA, R.C., 2008 7 SUMÁRIO 1. INTRODUÇÃO................................................................................................

ASSUNTO(S)

streptococcus mutans streptococcus mutans bothrops jararacussu bothrops moojeni bothrops jararacussu bothrops moojeni

ACESSO AO ARTIGO

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