Inherited haemoglobin variants in a South African population.
AUTOR(ES)
Bird, A R
RESUMO
We present the findings of a survey to determine the prevalence of inherited haemoglobin disorders in the Coloured (mixed ethnic origin) population of South Africa. A variety of haemoglobins was found. Of the structural variants, Hb E and Hb S were the most common, the former probably originating from South-East Asia and the latter from East Africa and possibly Madagascar. The alpha+ (-alpha) thalassaemia haplotype is particularly common with an observed frequency of 0.023. Beta thalassaemia was rather less common, while hereditary persistence of fetal haemoglobin was found for the first time in this population group, occurring in two subjects.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1049998Documentos Relacionados
- Osteoarthrosis in a rural South African Negro population.
- Rheumatoid arthritis in a rural South African Negro population.
- Rheumatoid arthritis in an urban South African Negro population.
- Serum uric acid concentrations in an urbanized South African Negro population.
- Molecular evidence that fragile X syndrome occurs in the South African black population.