Influence of Family History of Diabetes on Cardiac Autonomic Dysfunction of Adolescents
AUTOR(ES)
Dias-Filho, Carlos Alberto Alves; Soares Jr, Nivaldo de Jesus; Dias, Carlos José; Ferreira, Andressa Coelho; Sena, Carlan da Silva; Brito-Monzani, Janaína de Oliveira; Andrade, Rafael Martins; Vieira, Adeilson Serra Mendes; Pinto, Leandro Moraes; de Carvalho, Wellington Roberto G.; Mostarda, Cristiano Teixeira
FONTE
Int. J. Cardiovasc. Sci.
DATA DE PUBLICAÇÃO
2020-07
RESUMO
Abstract Background To evaluate cardiac autonomic modulation of adolescents with a family history of diabetic parents. Objective This study aims to evaluate the influence of a family history of diabetes on cardiac autonomic modulation. Methods This is an analytical and cross-sectional study on adolescents between 11 and 18 years of age, of both genders, who were divided into group with a family history of diabetes and a control group without a family history of diabetes. The study protocol consisted of the analysis of heart rate variability, blood pressure, anthropometric measurements, and body composition. Also, by using questionnaires, level of physical activity, sexual maturation, and sleep quality were evaluated. Normality of data distribution was tested using the Kolmogorov-Smirnov test. Then, statistical significance was evaluated using the Student's t-test, and the Cohen’s teste was used for calculation of the effect size. The level of significance adopted in the statistical analysis was 5%. Results When the group of individuals with a family history of diabetes was compared with the control group, statistically significant differences were observed in the variables the standard deviation of the NN time series interval (SDNN) (43.9 ± 2.2 vs. 53.5 ± 2.6 ms), the square root of the quadratic differences (RMSSD) (41.9 ± 3.3 vs. 52.4 ± 3.2 ms), standard deviation of beat-to-beat instantaneous variability (SD1) (29.7 ± 2.3 vs. 37.1 ± 2.3 ms), long-term standard deviation of continuous RR intervals (SD2) (. 54.1 ± 2.6 vs. 66.66 ± 3.5 ms), and in low frequency (LF) (496.0 ± 49.5 vs. 728 ± 71.6 ms2) and high frequency (HF) (1050.0 ± 120.4 vs. 737.4 ± 98.5 ms2) in the frequency domain. Conclusions Global autonomic modulation is decreased in adolescents with a family history of diabetes. We also observed a decrease in vagal activity in this group. So, sympathetic autonomic modulation is predominant in this population. (Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0)
Documentos Relacionados
- The assessment of cardiac autonomic functions in adolescents with a family history of premature atherosclerosis
- Influence of resistance training on cardiac autonomic modulation: literature review
- Autonomic dysfunction is common in liver cirrhosis and is associated with cardiac dysfunction and mortality: prospective observational study
- Autonomic nervous system dysfunction in children with severe tetanus: dissociation of cardiac and vascular sympathetic control
- Autonomic dysfunction in dementia