INDUCTION OF THE METHIONINE-ACTIVATING ENZYME IN SACCHAROMYCES CEREVISIAE1

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Pigg, C. JoAnne (Oregon State University, Corvallis), W. A. Sorsoli, and L. W. Parks. Induction of the methionine-activating enzyme in Saccharomyces cerevisiae. J. Bacteriol. 87:920–923. 1964.—The methionine-activating enzyme was induced in yeast in the presence of methionine, resulting in an accumulation of S-adenosylmethionine. Formation of the sulfonium derivative prevented the accumulation of high levels of free methionine in induced cells. The physiological significance of this phenomenon is discussed.

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