Induction of T Helper Type 1 Responses by a Polysaccharide Deacetylase from Cryptococcus neoformans
AUTOR(ES)
Biondo, Carmelo
FONTE
American Society for Microbiology
RESUMO
A 25-kDa cryptococcal deacetylase (d25) was found here to induce cell proliferation, as well as secretion of interleukin 2 and gamma interferon, but not interleukin 4, in spleen cells from d25-immunized or Cryptococcus neoformans-infected mice. The gamma interferon, but not the interleukin 2, response was required for the protective activities of d25 immunization in a murine cryptococcosis model.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=187367Documentos Relacionados
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