In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase

AUTOR(ES)

Gomes, Anne Caroline Candido, Sampaio, Luzia da Silva, Silva, Paulo André da, Lamas, Marcelo Einicker, Sakuragui, Cassia Mônica, Barreto Junior, Cleber Bomfim, Simas, Naomi Kato, Kuster, Ricardo Machado

FONTE

Quím. Nova

DATA DE PUBLICAÇÃO

2014

RESUMO

The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.

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