In-vitro cardiovascular protective activity of a new achillinoside from Achillea alpina
AUTOR(ES)
Zhou, Fei
FONTE
Rev. bras. farmacogn.
DATA DE PUBLICAÇÃO
17/10/2019
RESUMO
Abstract Achillinoside was isolated from methanol extract of Achillea alpina L., Asteraceae. The structure of the compound was characterized based on various spectrum data, including IR, HR-ESI-MS, 1D and 2D NMR. The cardiovascular protective effect of achillinoside was tested on H2O2-induced H9c2 cells. In our research, achillinoside could increase the cell viability dose-dependently in H2O2-induced H9c2 cells. In addition, the levels of caspase-3/9 cells were significantly decreased in H2O2 and achillinoside incubated H9c2 cells.
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