In vitro activity of LY146032 against staphylococci, streptococci, and enterococci.
AUTOR(ES)
Fass, R J
RESUMO
The in vitro activities of LY146032 and seven comparative antimicrobial agents against 14 species of staphylococci, streptococci, and enterococci were studied. MICs of LY146032 were less than or equal to 0.5 microgram/ml for all staphylococci, including oxacillin-resistant strains; less than or equal to 0.25 microgram/ml for all streptococci (except viridans group streptococci); and less than or equal to 4 micrograms/ml for all viridans group streptococci and enterococci. MICs were minimally affected by variations in inoculum size, and LY146032 was bactericidal against all species tested.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=176533Documentos Relacionados
- In vitro activity of RP 59500, a semisynthetic injectable pristinamycin, against staphylococci, streptococci, and enterococci.
- Effect of calcium on in vitro activity of LY146032 against Clostridium difficile.
- Activity of LY146032 in vitro and in experimental enterococcal pyelonephritis.
- Activity of LY146032 against Enterococci with and without high-level aminoglycoside resistance, including two penicillinase-producing strains.
- In vitro activity of LY146032 alone and in combination with other antibiotics against gram-positive bacteria.