Impaired Visual and Odor Recognition Memory Span in Patients With Hippocampal Lesions

AUTOR(ES)

Levy, Daniel A.

FONTE

Cold Spring Harbor Laboratory Press

RESUMO

In a recent study, rats with hippocampal lesions performed as well as did unoperated rats on an olfactory memory span task, performing ∼80% correct even when the span length reached 24 odors. This finding seems potentially at odds with demonstrations that memory-impaired patients typically fail tasks in which large amounts of information must be retained. Accordingly, we have assessed recognition memory span performance for line drawings of objects, designs, and odors in amnesic patients with damage thought to be limited to the hippocampal region. The patients were impaired on all three tasks. We consider possible explanations for the difference between the findings for humans and rats, including the fact that olfactory function is particularly well-developed in rodents.

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