Immunohistological features of synovitis in ankylosing spondylitis: a comparison with rheumatoid arthritis.
AUTOR(ES)
Kidd, B L
RESUMO
The immunohistological features of the synovial membrane in ankylosing spondylitis, HLA-B27 associated oligoarthritis, and rheumatoid arthritis wer examined with particular reference to T lymphocyte subsets. T helper (CD4+) cells clearly outnumbered T suppressor/cytotoxic (CD8+) cells in rheumatoid arthritis, whereas both cell types were present in equal numbers in ankylosing spondylitis. A reduction of CD4+/CD45R+ suppressor/inducer cells relative to CD4+/UCHL1+ helper/inducer cells was apparent in all diagnostic groups. The observations were suggestive of disease specific inflammatory responses within synovial membrane.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1003691Documentos Relacionados
- A comparison of serum biochemistry in ankylosing spondylitis, seronegative and seropositive rheumatoid arthritis.
- Faecal carriage of klebsiella by patients with ankylosing spondylitis and rheumatoid arthritis.
- HLA antigens in ankylosing spondylitis with peripheral arthritis.
- Ankylosing Spondylitis: A Survey
- Ankylosing Spondylitis: Review