Immunofluorescent localization of Tamm-Horsfall mucoprotein in human kidney
AUTOR(ES)
McKenzie, J. K.
RESUMO
A fluorescein-labelled antiserum to human Tamm-Horsfall mucoprotein applied to frozen human kidney sections gave strong specific labelling, mainly of cells of tubules in the outer medulla. By comparison with adjacent serial sections stained for alkaline phosphatase and succinic dehydrogenase, it is suggested that material reacting immunologically as Tamm-Horsfall muco-protein is found particularly in the cells of the ascending limb of the loop of Henle and the macula densa segment of the distal tubule.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=474080Documentos Relacionados
- Localization of Tamm-Horsfall glycoprotein in the human kidney using immuno-fluorescence and immuno-electron microscopical techniques.
- Localization of a single binding site for immunoglobulin light chains on human Tamm-Horsfall glycoprotein.
- Localization of Tamm-Horsfall glycoprotein in the normal rat kidney and the effect of adrenalectomy on its localization in the hamster and rat kidney.
- Role of Tamm-Horsfall protein and uromodulin in calcium oxalate crystallization
- Bladder pseudo-tumor: case report of vesical tamm-horsfall protein deposit