IL-13 and adenosine: partners in a molecular dance?

AUTOR(ES)

Grünig, Gabriele

FONTE

American Society for Clinical Investigation

RESUMO

Inflammation and airway remodeling are two responses readily apparent in asthma and other inflammatory disorders of the airway and lungs. Both adenosine and IL-13 play critical roles in contributing pathways. A new study reveals a previously unrecognized interaction between adenosine and IL-13 that indicates a mutual stimulation that may contribute to the nature and severity of airway inflammation and fibrosis.

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