Identification of Neutralizing Epitopes within Structural Domain III of the West Nile Virus Envelope Protein
AUTOR(ES)
Beasley, David W. C.
FONTE
American Society for Microbiology
RESUMO
Using a panel of neutralizing monoclonal antibodies, we have mapped epitopes in domain III of the envelope protein of the New York strain of West Nile virus. The ability of monoclonal antibodies that recognize these epitopes to neutralize virus appeared to differ between lineage I and II West Nile virus strains, and epitopes were located on the upper surface of domain III at residues E307, E330, and E332.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=136710Documentos Relacionados
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