Identification of hepatitis C virus subtype 2c by sequencing analysis in patients from Córdoba, Argentina
AUTOR(ES)
Ré, Viviana, Contigiani, Marta, Yoshida, Clara Fumiko Tachibana, Lampe, Elisabeth
FONTE
Memórias do Instituto Oswaldo Cruz
DATA DE PUBLICAÇÃO
2007-12
RESUMO
In Argentina, most information on hepatitis C virus (HCV) genotype distribution comes from studies carried out in Buenos Aires (east province). In order to identify HCV subtypes in central Argentina, nucleotide sequencing of core region was performed in samples from 36 patients living in Córdoba, the second most populated province of Argentina. The sequence analysis identified subtype 2c as the most prevalent (50%), followed by subtype 1b (33%) and to a lesser extent by subtypes 1a (11%), 3a (3%) and 4a (3%). This is the first report of circulation of HCV subtype 2c in this region of Argentina and also such high prevalence has never been found before in the genotype distribution of South America.
Documentos Relacionados
- Partial nucleotide sequencing of six subtype 2c hepatitis C viruses detected in Italy.
- First detection of Rio Negro virus (Venezuelan equine encephalitis complex subtype VI) in Córdoba, Argentina
- Mistyping of two Slovenian hepatitis C virus subtype 2c isolates as subtype 2b by two 5' noncoding region genotyping methods.
- Presence of a neutralizing domain in isolates of rubella virus in Cordoba, Argentina.
- Subtype 2c of hepatitis C virus is highly prevalent in Italy and is heterogeneous in the NS5A region.