Identification of Brucella abortus OxyR and Its Role in Control of Catalase Expression

AUTOR(ES)

Kim, Jeong-a

FONTE

American Society for Microbiology

RESUMO

We report the cloning and sequencing of the Brucella abortus oxyR homolog and provide evidence that the transcription product of this gene binds to the B. abortus catalase promoter region. A gene replacement/deletion Brucella oxyR mutant exhibits increased sensitivity to prolonged exposure to H2O2 and is unable to adapt to H2O2 in the environment.

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