Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy
AUTOR(ES)
Antunes, Hugo; Gil, Júlio; Marmelo, Bruno; Gonçalves, Maria Luísa; Pires, Maria Inês; Santos, João Miguel; Correia, Miguel; Cabral, José Costa
FONTE
Int. J. Cardiovasc. Sci.
DATA DE PUBLICAÇÃO
2020-12
RESUMO
Abstract A 72-year-old woman was admitted for acute heart failure. The echocardiography revealed moderate depression of the left ventricular ejection fraction. Coronary disease was excluded by coronarography. Cardiac magnetic resonance showed predominantly left ventricular septal hypertrophy and severe depression of the left ventricular systolic function. There was also a bright, multifocal and patchy late gadolinium enhancement with subendocardial, mesocardial and subepicardial involvement, suggestive of sarcoidosis. Biochemical study, thoracic computed tomography and positron emission tomography were inconclusive for extra-cardiac sarcoidosis. Therefore, an endomyocardial biopsy was performed. The procedure was complicated by the development of complete atrioventricular block, requiring implantation of a cardiac resynchronization pacing device. A few days after device implantation, the patient developed fever. The echocardiography revealed extensive vegetations, and thus the diagnosis of a device-associated infective endocarditis was made. Even though antibiotic therapy was promptly started, the patient ended up dying. Biopsy results revealed lymphocytic myocarditis. This case is paradigmatic because it shows how the etiologic diagnosis of dilated cardiomyopathy can be challenging. Non-invasive diagnostic exams may not provide a definite diagnosis, requiring an endomyocardial biopsy. However, the benefits versus risks of such procedure must always be carefully weighted.
Documentos Relacionados
- Diagnostic work-up of gastroenteropancreatic neuroendocrine tumors
- A young man with position-dependent erectile dysfunction: diagnostic work-up and interventional therapy of an arteriovenous malformation
- Genetic work-up of hereditary spastic paraplegias is crucial for classifying these disorders
- Symptomatic Aortic Valve Mass - Cardiac Work-Up Challenges and Role of Computed Tomography Angiography: A Case Report
- EMBOLIC COMPLICATIONS OF CARDIOMYOPATHY