Hypogammaglobulinemia and Thymic Hypoplasia in Horses: a Primary Combined Immunodeficiency Disorder
AUTOR(ES)
McGuire, T. C.
RESUMO
A severe combined immunodeficiency disorder was demonstrated in two Arabian foals which were full siblings. The defect in the B-lymphocyte system was shown by hypogammaglobulinemia, lymphopenia, and absence of germinal centers. The almost total absence of thymic tissue in one foal and the lack of thymic dependent lymphocytes in the spleens of both foals demonstrate a T-lymphocyte defect. In a retrospective study of total available Arabian foal cases, 4 of 15 had evidence of immunodeficiency.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=422843Documentos Relacionados
- Thymic activity in severe combined immunodeficiency diseases.
- Persistent cryptosporidiosis in horses with severe combined immunodeficiency.
- Salivary syndrome in horses: identification of slaframine in red clover hay.
- In vitro of adenosine on lymphocytes and erythrocytes from horses with combined immunodeficiency.
- Salmonella in horses: a source of contamination of horsemeat in a packing plant under federal inspection.
