Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens
AUTOR(ES)
Peres, Daniela D'Almeida, Hubner, Alexandra, Oliveira, Camila Areias de, Almeida, Tania Santos de, Kaneko, Telma Mary, Consiglieri, Vladi Olga, Pinto, Claudinéia Aparecida Sales de Oliveira, Velasco, Maria Valéria Robles, Baby, André Rolim
FONTE
Braz. J. Pharm. Sci.
DATA DE PUBLICAÇÃO
22/06/2017
RESUMO
ABSTRACT The chronological skin aging is a progressive and natural process with genetic and physiological changes. However, ultraviolet (UV) radiation may accelerate the oxidative stress, generating carcinogenesis and photoaging. Natural compounds and their applications are considered a trend in the cosmetic market. The protein-based film-forming compounds play an important role, once it collaborates for the better distribution of sunscreens on the skin. Here we investigated the in vitro photoprotective effectiveness of sunscreens containing the hydrolyzed collagen associated with UVA, UVB and/or inorganic filters. Sunscreens were developed with octocrylene (7.5%), butyl methoxydibenzoylmethane (avobenzone) (3.0%) and/or titanium dioxide (5.0%), associated or not with the hydrolyzed collagen (3.0%). In vitro photoprotective effectiveness was determined in a Labsphere(r) UV2000S by the establishment of the sun protection factor (SPF) and critical wavelength (nm) values. Physicochemical and organoleptic characteristics were also assayed. The hydrolyzed collagen subjectively improved the formulation sensory characteristics. However, this bioactive compound led to a decrease of the SPF values of the photoprotective formulations containing octocrylene alone and octocrylene + butyl methoxydibenzoylmethane + TiO2. This inadequate interaction may be considered during the development of new sunscreens intended to contain protein-based components.
Documentos Relacionados
- Treatment time of ultrasound therapy interferes with the organization of collagen fibers in rat tendons
- Influence of particle size on appearance and in vitro efficacy of sunscreens
- Expression of slime interferes with in vitro detection of host protein receptors of Staphylococcus epidermidis.
- In vitro and in vivo evaluation of efficacy and safety of photoprotective formulations containing antioxidant extracts
- In vitro photoprotective effects of Marcetia taxifolia ethanolic extract and its potential for sunscreen formulations