Human protein reference database as a discovery resource for proteomics
AUTOR(ES)
Peri, Suraj
FONTE
Oxford University Press
RESUMO
The rapid pace at which genomic and proteomic data is being generated necessitates the development of tools and resources for managing data that allow integration of information from disparate sources. The Human Protein Reference Database (http://www.hprd.org) is a web-based resource based on open source technologies for protein information about several aspects of human proteins including protein–protein interactions, post-translational modifications, enzyme–substrate relationships and disease associations. This information was derived manually by a critical reading of the published literature by expert biologists and through bioinformatics analyses of the protein sequence. This database will assist in biomedical discoveries by serving as a resource of genomic and proteomic information and providing an integrated view of sequence, structure, function and protein networks in health and disease.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=308804Documentos Relacionados
- Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans
- The Homeodomain Resource: a prototype database for a large protein family
- A HyperCard-shell for the human genome mapping database (HGM) including a stand-alone reference database.
- Protein Identification False Discovery Rates for Very Large Proteomics Data Sets Generated by Tandem Mass Spectrometry*
- PEDRo: A database for storing, searching and disseminating experimental proteomics data
