Human Papillomavirus Type 16 E7 Oncoprotein Represses Transcription of Human Fibronectin
AUTOR(ES)
Rey, Osvaldo
FONTE
American Society for Microbiology
RESUMO
The E7 oncoprotein encoded by human papillomavirus (HPV) type 16 repressed the transcription of fibronectin, a key component of the extracellular matrix. This repression, detected in several HPV-positive nontumorigenic and tumorigenic cell lines, was abolished when the Cys-X-X-Cys repeats in E7 were disrupted.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=112019Documentos Relacionados
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