How generalised are secondarily “generalised” tonic–clonic seizures?
AUTOR(ES)
Schindler, Kaspar
FONTE
BMJ Group
RESUMO
In clinical practice, epileptic seizures with focal onset and subsequent generalised motor involvement are referred to as secondarily generalised seizures. The purpose of this study was to investigate the degree of electrophysiological generalisation in seizures that are clinically secondarily generalised. Intracranial EEG recordings of secondarily generalised tonic–clonic seizures were visually and quantitatively analysed for the presence of epileptiform activity. In 24 (26%) of 93 seizures recorded from 17 (27%) of 64 patients, intracranial EEG channels were found that never recorded epileptiform activity during secondarily generalised tonic–clonic seizures. Our results demonstrate that seizures that are secondarily generalised clinically are not always generalised electrophysiologically. This may have therapeutic implications.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2117860Documentos Relacionados
- Clinical use of ictal SPECT in secondarily generalized tonic–clonic seizures
- Tonic-clonic seizures in patients taking sildenafil
- The comparative efficacy of antiepileptic drugs for partial and tonic-clonic seizures.
- Visual contrast sensitivity in tonic-clonic epileptic patients
- Carbamazepine in the treatment of generalised tonic clonic seizures in juvenile myoclonic epilepsy.
