Host-Cell Lysosomal Response to Two Strains of Herpes Simplex Virus 1
AUTOR(ES)
Fine, D. L.
RESUMO
A correlation has been made between the host lysosomal responses to and release of infectious virus from HEp-2 cells infected with two strains of herpes simplex virus (HSV). Supravital staining with acridine orange was used for morphological studies of macroplaque and microplaque HSV-infected cells. With the progression of infection, cells infected with either microplaque HSV or macroplaque HSV were observed to undergo different lysosomal and cytopathic changes, which could be correlated with increased accumulation of acid phosphatase and infectious virus in the extracellular fluid.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=375991Documentos Relacionados
- Vaccinia Virus Replication I. Requirement for the Host-Cell Nucleus
- Factors Enhancing the Host-Cell Penetration of Toxoplasma gondii
- Inhibition of Host-Cell Protein and Ribonucleic Acid Synthesis by Newcastle Disease Virus
- A hitchhiker's guide to cell biology: exploitation of host-cell functions by intracellular pathogens
- Role of Adenovirus Structural Proteins in the Cessation of Host-Cell Biosynthetic Functions 1
