High Levels of Resistance to Metronidazole and Clarithromycin in Helicobacter pylori Strains in Children
AUTOR(ES)
Kalach, Nicolas
FONTE
American Society for Microbiology
RESUMO
The aim of the study was to evaluate the prevalence of resistance to amoxicillin, metronidazole, and clarithromycin before treatment of Helicobacter pylori infection in children and to assess the evolution of resistance with time. The study was carried out between 1994 and 1999 with 150 H. pylori-positive children through gastric culture (antimicrobial susceptibility) and histology. All cultured H. pylori strains were sensitive to amoxicillin, 64 (43%) were resistant to metronidazole, 32 (21%) were resistant to clarithromycin, and 14 (9%) were resistant to both metronidazole and clarithromycin. The overall prevalence of resistance to metronidazole and clarithromycin did not change significantly with time. The study highlights the generalized high-level and stable metronidazole and clarithromycin resistance of H. pylori strains from children.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=87742Documentos Relacionados
- Helicobacter pylori Primary Resistance to Metronidazole and Clarithromycin in Brazil
- Risk of Development of In Vitro Resistance to Amoxicillin, Clarithromycin, and Metronidazole in Helicobacter pylori
- Clarithromycin Resistance and Eradication of Helicobacter pylori in Children
- Regional Differences in Metronidazole Resistance and Increasing Clarithromycin Resistance among Helicobacter pylori Isolates from Japan
- Universal High-Level Primary Metronidazole Resistance in Helicobacter pylori Isolated from Children in Egypt
