Grinding and Milling: Two Efficient Methodologies in the Solvent-Free Phosphomolybdic Acid-Catalyzed and Mechanochemical Synthesis of cis-4-Amido-N-yl-2-methyl-tetrahydroquinolines
AUTOR(ES)
Kouznetsov, Vladimir V., Merchán-Arenas, Diego R., Martínez-Bonilla, Carlos A., Macías, Mario A., Roussel, Pascal, Gauthier, Gilles H.
FONTE
J. Braz. Chem. Soc.
DATA DE PUBLICAÇÃO
2016-12
RESUMO
The ball-milling process of ABB' Povarov reaction through mechano-chemical activation with phosphomolybdic acid (PMA) as heteropolyacid (HPA) catalyst, was first time explored. The developed high speed vibratory ball milling (HSVBM) green method offers simple and efficient diastereoselective synthesis of cis-2,4-disubstituted tetrahydroquinolines in good to excellent yields (56-76%).
Documentos Relacionados
- Indium(III)-catalyzed synthesis of N-substituted pyrroles under solvent-free conditions
- A general and efficient synthesis of pyrazoles catalyzed by Sc(OTf)3 under solvent-free conditions
- Efficient synthesis of sulfonamide derivatives on solid supports catalyzed using solvent-free and microwave-assisted methods
- Microwave accelerated solvent-free synthesis of flavanones
- Pyrazole synthesis under microwave irradiation and solvent-free conditions
