Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
AUTOR(ES)
Zanella, Louise, Pina-Araujo I, Isabel de, Morgado, Mariza G, Vicente, Ana Carolina
FONTE
Mem. Inst. Oswaldo Cruz
DATA DE PUBLICAÇÃO
2016-09
RESUMO
We characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution.
Documentos Relacionados
- Genome-Wide Analyses of Avian Sarcoma Virus Integration Sites
- Genome-wide transcription analyses in Mycobacterium tuberculosis treated with lupulone
- Genome-wide somatic hypermutation
- A Genome-Wide Survey of Human Pseudogenes
- Genome-Wide Expression Analyses of Gene Regulation during Early Development of Dictyostelium discoideum