Genome scans and microarrays: converging on genes for schizophrenia?

AUTOR(ES)

Williams, Nigel M

FONTE

BioMed Central

RESUMO

Systematic genome-wide scans to date have shown that genes of major effect are not common causes of schizophrenia, but independent linkage studies looking for schizophrenia susceptibility genes are converging on a number of key chromosomal locations. Microarray expression analysis may identify new candidate genes and pathways, and a number of intriguing preliminary findings have already been reported.

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