Genetic Control of the Cell Division Cycle in Yeast: V. Genetic Analysis of cdc Mutants

AUTOR(ES)

Hartwell, Leland H.

RESUMO

One hundred and forty-eight temperature-sensitive cell division cycle (cdc) mutants of Saccharomyces cerevisiae have been isolated and characterized. Complementation studies ordered these recessive mutations into 32 groups and tetrad analysis revealed that each of these groups defines a single nuclear gene. Fourteen of these genes have been located on the yeast genetic map. Functionally related cistrons are not tightly clustered.

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