Genetic Characterization of Antimicrobial Resistance in Canadian Isolates of Salmonella Serovar Typhimurium DT104
AUTOR(ES)
Ng, Lai-King
FONTE
American Society for Microbiology
RESUMO
PCR was used to identify antibiotic resistance determinants in 31 Canadian Salmonella serovar Typhimurium DT104 isolates. Genes encoding resistance to ampicillin (pse1 or blaP1), chloramphenicol (pasppflo-like), streptomycin-spectinomycin (aadA2), sulfonamide (sulI), and tetracycline [tet(G)] were mapped to a 13-kb region of DNA of one isolate. Two copies of sulI were identified and mapped to the 3′ end of either pse1 or aadA2 integrons. The two integrons were separated by the pasppflo-like gene and the tet(G) gene. The kanamycin resistance determinant (aphA-1) was present on a 2.0-MDa plasmid (five isolates) or on the chromosome (three isolates).
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89607Documentos Relacionados
- Multiple Antibiotic Resistance (mar) Locus in Salmonella enterica Serovar Typhimurium DT104
- Salmonella enterica Serovar Typhimurium DT104 Displays a Rugose Phenotype†
- Molecular Characterization of an Antibiotic Resistance Gene Cluster of Salmonella typhimurium DT104
- AcrAB-TolC Directs Efflux-Mediated Multidrug Resistance in Salmonella enterica Serovar Typhimurium DT104
- In Vitro and In Vivo Assessment of Salmonella enterica Serovar Typhimurium DT104 Virulence