Genetic and physiological control of host cell lysis by bacteriophage lambda.
AUTOR(ES)
Rolfe, B G
RESUMO
The timing of host cell lysis at the end of the lytic cycle of phage lambda is under complex control. The lambda S protein stimulates lysis. Another physiological system, the lysis regulator, inhibitis lysis from occurring prematurely. The effects of a series of phage and bacterial mutations on these controls are described. They show that the lambda rex gene plays a role in regulating lysis under suboptimal growth conditions. In certain mutant cells, and especially under anaerobic culture conditions, the rex gene aids in the scheduling of host cell lysis. The data also suggest that the lysis regulator may control the transition of the lambda S protein from an inactive to an active state.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=515874Documentos Relacionados
- S gene expression and the timing of lysis by bacteriophage lambda.
- Genetic map of bacteriophage lambda.
- Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda.
- Genetic and DNA mapping of the late regulation and lysis genes of Salmonella bacteriophage P22 and coliphage lambda.
- Control of bacteriophage lambda CII activity by bacteriophage and host functions.