Genetic ancestry of patients with porphyria cutanea tarda in a country with mixed races: a cross-sectional study (Rio de Janeiro - Brazil)

AUTOR(ES)

Succi, Isabella Brasil, Pôrto, Luís Cristóvão, Domingues, Patricia Mariana Gonçalves da Rocha Porto, Fonseca, João Carlos Macedo

FONTE

An. Bras. Dermatol.

DATA DE PUBLICAÇÃO

2018-02

RESUMO

Abstract: Porphyria cutanea tarda has a complex etiology with genetic factors not completely elucidated. The miscegenation of the Brazilian population has important implications in the predisposition to diseases. There are no studies concerning the genetic ancestry of patients with porphyria cutanea tarda from a mixed population. Thirty patients living in Rio de Janeiro with sporadic porphyria cutanea tarda were studied for the genetic ancestry through informative markers - INDELS. There was a significant predominance of European ancestry across the sample of patients with porphyria cutanea tarda (70.2%), and a small contribution of African and Amerindian ancestry, 20.1% and 10.9%, respectively.

Documentos Relacionados

• Sporotrichoid leishmaniasis: a cross-sectional clinical, epidemiological and laboratory study in Rio de Janeiro State, Brazil
• Psychiatric emergency units in Brazil: a cross-sectional study
• Antiphospholipid antibodies in vascular surgery patients. A cross-sectional study.
• Audiological Abnormalities in Vitiligo Patients: A Hospital-Based Cross-Sectional Study
• Factors associated with adherence to antiretroviral therapy in HIV/AIDS patients: a cross-sectional study in Southern Brazil