Gene Dosage and Linezolid Resistance in Enterococcus faecium and Enterococcus faecalis

AUTOR(ES)

Marshall, S. H.

FONTE

American Society for Microbiology

RESUMO

Resistance to linezolid has been associated with a G2576U mutation in domain V of the 23S rRNA. We analyzed nine clinical isolates of linezolid-resistant enterococci and showed a clear association between the number of 23S rRNA genes containing this mutation and the level of linezolid resistance expressed.

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