Gender differences of cannabis smoking on serum leptin levels: population-based study

AUTOR(ES)

Moreira, Fernanda P., Wiener, Carolina D., Oliveira, Jacqueline F. de, Souza, Luciano D.M., da Silva, Ricardo A., Portela, Luis V., Lara, Diogo R., Jansen, Karen, Oses, Jean Pierre

FONTE

Rev. Bras. Psiquiatr.

DATA DE PUBLICAÇÃO

01/02/2018

RESUMO

Objective: To evaluate the serum leptin levels in cannabis smokers. Methods: This was a cross-sectional population-based study of participants between the ages of 18 and 35 years. The data were collected through a self-administered questionnaire covering sociodemographic data and the use of psychoactive substances. Leptin levels were measured using a commercial ELISA kit. Results: Of the 911 participants, 6.7% were identified as cannabis smokers and had significantly lower leptin levels (p = 0.008). When stratified by gender, there was a significant decrease in leptin levels among male smokers (p = 0.039). Conclusion: Cannabis smoking was linked to leptin levels in men, suggesting that the response to biological signals may be different between men and women.

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