G26P[19] rotavirus A strain causing acute gastroenteritis in the American continent
AUTOR(ES)
Gómez, Mariela M, Silva, Marcelle FM da, Volotão, Eduardo M, Fialho, Alexandre M, Mazzoco, Christian S, Rocha, Myrna S, Leite, José Paulo G
FONTE
Mem. Inst. Oswaldo Cruz
DATA DE PUBLICAÇÃO
29/11/2018
RESUMO
In Brazil, the rotavirus A genotype G26 was first identified in suckling piglets, while the P[19] genotype has not been identified in any animal species so far. This report details the genetic characterisation of a G26P[19] RVA strain detected from an eight year-old child, vaccinated with Rotarix®, hospitalised with acute diarrhoeal disease in Rio de Janeiro in 2015. Most likely, the genome constellation (I5-R1-C1-M1-A8-N1-T1-E1-H1) observed in the G26P[19] Brazilian strain was a result of interspecies transmission events between humans and pigs. In addition, a rearrangement in the NSP5 gene was observed downstream of the 3’ non-coding region.
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