Function of S-adenosylmethionine in germinating yeast ascospores.
AUTOR(ES)
Choih, S J
RESUMO
Germination and outgrowth of ascospores of Saccharomyces cerevisiae 4579 require both methionine and adenine, whereas leucine is only required for outgrowth. The methionine requirement may be satisfied by S-adenosylmethionine, but this sulfonium compound will not substitute for adenine. Between 30 and 70 min of protein synthesis is initially required for the completion of germination in strain 4579. The inhibition of S-adenosylmethionine synthetase by trifluoromethionine prevents both germination and protein synthesis. During the initial stages of germination, the S-adenosylmethionine synthetase, S-adenosylmethionine decarboxylase, and transfer ribonucleic acid methyltransferases increased significantly, indicating that polyamines and/or the methylation of transfer ribonucleic acid are required for the initiation of germination.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=235391Documentos Relacionados
- Role of S-Adenosylmethionine in Methionine Biosynthesis in Yeast
- The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain
- Relationship between polyamines and macromolecules in germinating yeast ascospores.
- S-Adenosylmethionine Transport in Rickettsia prowazekii
- Transport of S-Adenosylmethionine in Saccharomyces cerevisiae