From co-expression to co-regulation: how many microarray experiments do we need?

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BioMed Central

RESUMO

The ability to identify co-regulated genes from microarray clustering results is strongly dependent on the number of microarray experiments used in cluster analysis and the accuracy of these associations plateaus at between 50 and 100 experiments on yeast data. Even with large numbers of experiments, the false positive rate may exceed the true positive rate.

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