Frequency of Resistance to Kanamycin, Tobramycin, Netilmicin, and Amikacin in Gentamicin-Resistant Gram-Negative Bacteria

AUTOR(ES)

Seligman, Stephen J.

RESUMO

In vitro evaluation of 66 epidemiologically distinct, gentamicin-resistant, gram-negative isolates from four hospitals revealed that 92% were kanamycin resistant, 44% were netilmicin resistant, 41% were tobramycin resistant, and 6% were amikacin resistant. Combined resistance to gentamicin, tobramycin, and netilmicin occurred in 30% of the strains. Although the resistance percentage to amikacin was the lowest of the three newer agents, two strains were resistant to all of the aminoglycosides tested.

Documentos Relacionados

• Surveillance of Gentamicin-Resistant Gram-Negative Bacilli in a General Hospital
• Renal disposition of gentamicin, dibekacin, tobramycin, netilmicin, and amikacin in humans.
• Endogenous colonization by gentamicin-resistant gram-negative bacilli elaborating aminoglycoside (3)-5-acetyltransferase.
• Amifloxacin activity against well-defined gentamicin-resistant, gram-negative bacteria.
• In Vitro Activity of Netilmicin Compared with Gentamicin, Tobramycin, Amikacin, and Kanamycin