Frequency, intensity, species, and strains of oral Candida vary as a function of host age.
AUTOR(ES)
Kleinegger, C L
RESUMO
While the age of the host has been suggested as a determining factor in yeast carriage, no studies in which the genetic relatedness of isolates has been assessed in combination with the frequency and intensity of carriage as a function of host age have been performed in a single geographical locale and over a short time window. Therefore, by using a simple plating protocol to determine the frequency and intensity of carriage, sugar assimilation patterns to determine species, and Southern blot hybridization with the DNA fingerprinting probe Ca3 combined with computer-assisted analysis to determine the genetic relatedness of strains of Candida albicans, yeast carriage was analyzed as a function of age. All test individuals lived in the Iowa City, Iowa, locale and, except for some of the 0.5- to 1.5-year-olds, were dentate. The results demonstrate that for this test population, the frequency, average intensity, predominant species, and genetic relatedness of C. albicans strains varied as a function of host age. In addition, comparison with oral commensal organisms from the Ann Arbor, Mich., locale confirms the geographical specificity of C. albicans strains and the existence of an Iowa City-enriched strain which is most prevalent in elderly individuals.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=229226Documentos Relacionados
- Carriage Frequency, Intensity of Carriage, and Strains of Oral Yeast Species Vary in the Progression to Oral Candidiasis in Human Immunodeficiency Virus-Positive Individuals
- The effects of intensity, frequency, static load, and shore hardness on different parameters in vibration sensitivity measurements.
- Development of Antibody Isotype Responses to Schistosoma mansoni in an Immunologically Naive Immigrant Population: Influence of Infection Duration, Infection Intensity, and Host Age
- Prevalence of Candida Species, Including Candida dubliniensis, in Singapore
- Biochemical localization of the alkaline phosphatase of Bacillus licheniformis as a function of culture age.