Falsely elevated serum estradiol due to heterophile antibody interference: a case report
AUTOR(ES)
Atkins, Paul; Mattman, Andre; Thompson, David
FONTE
Arch. Endocrinol. Metab.
DATA DE PUBLICAÇÃO
2021-04
RESUMO
SUMMARY Falsely elevated estradiol is rare, may result from heterophile antibody interference, and can result in unnecessary investigation and intervention. We present the case of a 56-year-old female with falsely elevated estradiol levels inconsistent with her overall clinical picture, which ultimately led to an unnecessary surgical procedure. With the use of alternative analytical platforms and a heterophile antibody blocking agent, we determined the false elevation was due to heterophile antibody interference. Clinicians must suspect and investigate for laboratory error when the clinical picture contradicts laboratory results.
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