Failure To Detect Chlamydia pneumoniae in Brain Sections of Alzheimer's Disease Patients
AUTOR(ES)
Gieffers, Jens
FONTE
American Society for Microbiology
RESUMO
A recent North American study detected Chlamydia pneumoniae in 17 of 19 brains of Alzheimer's patients and supposed a C. pneumoniae infection to be a risk factor for Alzheimer's disease (AD). In this study, we analyzed paraffin-embedded tissue samples of 20 AD patients by nested PCR and immunocytochemistry with a panel of antichlamydial antibodies and could detect neither C. pneumoniae-specific DNA nor chlamydial antigens. From our data, the presence of C. pneumoniae in the brains of Alzheimer's patients is not a common phenomenon; an association remains questionable.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=86233Documentos Relacionados
- Failure To Detect Chlamydia pneumoniae in the Late-Onset Alzheimer's Brain
- PCR Search for the Herpes Simplex Virus Type 1 Genome in Brain Sections of Patients with Familial Alzheimer's Disease
- Screening patients for Alzheimer's disease.
- Assessing Vision in Patients With Alzheimer's Disease
- Aging of the Brain and Alzheimer's Disease. (Progress in Brain Research Vol 70.)
