Extensively drug-resistant tuberculosis: a case report and literature review

AUTOR(ES)

Araújo-Filho, João Alves de, Vasconcelos-Jr, Arioldo Carvalho, Sousa, Eduardo Martins de, Silveira, Colombina da, Ribeiro, Elisangela, Kipnis, André, Junqueira-Kipnis, Ana Paula

FONTE

Brazilian Journal of Infectious Diseases

DATA DE PUBLICAÇÃO

2008-10

RESUMO

Extensively drug-resistant tuberculosis (XDR-TB) is an emerging health problem that threatens tuberculosis (TB) control worldwide, since suitable treatment for this disease has not yet been found. We report a case of secondary pulmonary XDR-TB in a 54-year-old, HIV-negative male from Goiânia, Brazil. The patient had long-standing pulmonary tuberculosis (nine years) with extensive bilateral lung damage and had been treated with multiple antituberculosis drugs (self-administered) before XDR-TB diagnosis. The strain of Mycobacterium tuberculosis was resistant to R- rifampicin, H-isoniazid, E-ethambutol, Eto-ethionamide, Ofx-ofloxacin, and Am-amikacin. This patient died with multiple organ failure due to sepsis secondary to bacterial pneumonia.

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