Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents

AUTOR(ES)

Souza, William Marciel de, Machado, Alex Martins, Figueiredo, Luiz Tadeu Moraes

FONTE

Mem. Inst. Oswaldo Cruz

DATA DE PUBLICAÇÃO

24/05/2016

RESUMO

This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.

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